What is Regvar?

Regvar is a deep neural network-based computational framework for prioritizing tissue-specific regulatory impact of human noncoding SNPs on their potential target genes. RegVar integrates the sequential, epigenetic and evolutionary conservation profiles of SNPs and their potential target genes in 17 human tissues, and give tissue-specific predictions of regulatory probabilities of the provided SNPs on provided genes.

Please enter the information below to run RegVar analysis.

Email address you want the results sent to (Suggested).

Upload a file containing a list of SNPs and genes:

A text file containing a list of SNP IDs and their possible genes is needed to be uploaded to the server for batch analysis. The result will be generated based on all possible permutations of the SNPs and genes no more than 10,000 valid pairs.

Click here to see an example file: BED

Or type SNP ID(s) and gene(s) in the corresponding search boxes:

SNP ID(s) (indels are currently not supported) and their possible target gene(s) are accepted as input in the SNPs and Gene search box, respectively. Multiple SNP IDs or genes should be delimited by commas, spaces or tabs, and if so, the result will be generated based on the all possible permutations of the SNPs and genes.